Continuous saline bladder irrigation for two hours following transurethral resection of bladder tumors in patients with non-muscle invasive bladder cancer does not prevent recurrence or progression compared with intravesical Mitomycin-C

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Continuous saline bladder irrigation after transurethral resection is a prophylactic treatment choice for non-muscle invasive bladder tumor.

BACKGROUND Instillation of chemotherapy after transurethral resection (TUR) has been considered as an optimal treatment for non-muscle invasive bladder cancer (NMIBC). However, controversy remains regarding the role of chemotherapy instillation. We therefore evaluated the usefulness of continuous saline bladder irrigation (CSBI) after TUR. PATIENTS AND METHODS Patients with intermediate risk ...

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Single instillation of mitomycin C reduces 1st year recurrence following transurethral resection of non-muscle invasive bladder cancer.

OBJECTIVE To study the impact of single instillation of 40 mg Mitomycin C (MMC-40) within first hour of transurethral resection (TUR), on first year recurrence of non-muscle invasive bladder cancer. METHODS In this study of two groups of patients with similar demographics and tumour profile were compared to assess first year tumour recurrence pattern. Group A received MMC-40 within 30 minutes...

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Repeated transurethral resection for non-muscle invasive bladder cancer.

BACKGROUND transurethral resection of bladder tumor (TURBT) is the first-line treatment fornon-muscle-invasive bladder cancer. We aimed to investigate the effect of probable risk factors on the positive rate of the repeated transurethral resection of bladder tumor performed 4-6 weeks after an initial TURBT in patients with non-muscle invasive bladder cancer in China. METHODS 134 patients with...

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Therapies in bladder cancer: intravesical mitomycin-C

The use of intravesical therapy for the treatment of superficial bladder cancer aims to reduce morbidity and mortality by eradicating existing disease, preventing tumor recurrence and attempting to halt tumor progression. Mitomycin-C is a commonly used intravesical treatment option for superficial bladder cancer and was used for the first time by Shida and colleagues in 1967 [1]. It is an antit...

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Predicting recurrence of non-muscle-invasive bladder cancer after transurethral resection.

AIM To determine clinical prognostic factors and their impact on the risk of recurrence of newly discovered non-muscle-invasive bladder cancer. METHODS The study included 120 patients of both sexes aged 45-80 years with newly discovered non-muscle-invasive bladder cancer. All the patients were treated surgically by transurethral electro resection (TUER). The outcome of patients with and witho...

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ژورنال

عنوان ژورنال: BMC Urology

سال: 2018

ISSN: 1471-2490

DOI: 10.1186/s12894-018-0408-6